The lives of the support crew serving on one of Starfleet's least important ships, the U.S.S. Cerritos, in 2380. Ensigns Mariner, Boimler, Rutherford and Tendi have to keep up with their duties and their social lives, often while the ship is being rocked by a multitude of sci-fi anomalies.

• Tawny Newsome
• Jack Quaid
• Noël Wells
• Eugene Cordero
• Dawnn Lewis
• Gillian Vigman
• Jerry O'Connell
• Fred Tatasciore