Fresh Meat is the 12th season of the MTV reality game show, The Challenge. Fresh Meat is a season that made history on The Challenge by being the first season to include previously unknown contestants as part of the cast. Previous to Fresh Meat, all seasons functioned solely by the program's trademark: strictly using contestants that were previously cast on past seasons of The Real World or Road Rules. To date, Fresh Meat's most notable debuting contestants who've both continued on in further seasons of the show and won Challenge seasons are: Kenny Santucci, Evelyn Smith, and Evan Starkman. Filmed in Australia, Fresh Meat featured two-player teams; each team had an alumnus of The Real World or Road Rules partnered with a newcomer to the Challenge. This is the first edition of the Fresh Meat series, with Fresh Meat II following in 2010.

• Darrell Taylor
• Devin Walker-Molaghan
• Horacio Gutiérrez
• Johnny 'Bananas' Devenanzio
• Jordan Wiseley
• Aneesa Ferreira
• Kaycee Clark
• Laurel Stucky