The lives of several people spanning from 1936 to 1993 are chronicled during their overnight stay at a New York City hotel room.

• Clark Heathcliffe Brolly
• Camilla Overbye Roos
• Glenne Headly
• Harry Dean Stanton
• Freddie Jones
• Griffin Dunne
• Deborah Kara Unger
• Mariska Hargitay