Rescue Me revolves around the lives of the men in a New York City firehouse, the crew of 62 Truck. Examining the fraternal nature and relationships of firefighters, the series tackles the daily drama of the life-and-death situations associated with being a firefighter, while exploring the ways the men use dark humor to protect their true emotions.

• Denis Leary
• Adam Ferrara
• Andrea Roth
• John Scurti
• Daniel Sunjata
• Michael Lombardi
• Steven Pasquale
• Larenz Tate