Focuses on a group of toddlers, most prominently Tommy, Chuckie, Phil, Lil, and Angelica, and their day-to-day lives, usually involving common life experiences that become adventures in the babies' imaginations. Adults in the series are almost always unaware of what the children are up to; however, this only provides more room for the babies to explore and discover their surroundings.

• Elizabeth Daily
• Kath Soucie
• Cheryl Chase
• Dionne Quan
• Tara Strong
• Joe Alaskey
• Melanie Chartoff
• Tress MacNeille