The charming and still-single Joey has struck out on his own and moved to Hollywood, hoping to truly make it as an actor. After reuniting with his high-strung sister Gina, Joey moves in with Michael, his 20-year-old genius nephew, who unbelievably is literally a rocket scientist. However, what Joey lacks in book smarts he makes up for with people smarts – making him the best new friend his nephew could ask for.

• Matt LeBlanc
• Drea de Matteo
• Andrea Anders
• Paulo Costanzo
• Jennifer Coolidge
• Miguel A. Núñez Jr.