In the reign of Emperor Taizong (627—649),which was called the Prosperity of Zhenguan, former clothing maker An is framed and imprisoned. When she was in danger, she entrusts her young daughter Liu Li to an old friend in the palace. Liu Li grows up in the palace and becomes a medical officer, responsible for epidemic prevention.

• Guli Nazha
• Timmy Xu
• Zhao Shunran
• Liu Duanduan
• Zeng Yixuan
• Zhang Tao
• Zhu Rui
• Song Hanyu