Buffalo Bill and Wild Bill Hickok join forces to establish a mail route that can get mail from St. Joseph, Missouri, to Sacramento, California, in ten days. Along the way they must battle bad weather, hostile Indians and outlaws intent on robbing the mail and shutting down the entire operation.

• Nat Holt Productions
• Charlton Heston
• Rhonda Fleming
• Jan Sterling
• Forrest Tucker
• Porter Hall
• Henry Brandon
• Richard Shannon
• Stuart Randall